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The mAbXmise quantification kits are intended to monitor the concentration of therapeutic monoclonal antibodies (mAbs) in samples from patients treated with these mAbs. The kit is a quantitative assay. The test can be performed on plasma (EDTA, heparin or citrate collection tubes) and serum. Assay results are intended to be used by healthcare professionals. Before use, it is important to carefully read the instructions provided with the product.
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mAbXmise monoclonal antibodies quantification kits are In Vitro Diagnostic Medical Devices for laboratory professional use and CE-IVD labeled for Europe by BSI. Assay results are intended to be used by healthcare professionals. The kits are designed to perform absolute quantification by LC-MS (Liquid Chromatography – Mass spectrometry) of specific therapeutic monoclonal antibodies (mAbs) in a patient sample. Assay results are intended to be used by healthcare professionals. Before use, it is important to carefully read the instructions provided with the product. The products are non-refundable. The mAbXmise Kit described has not been cleared by any regulatory entity for diagnostic purposes outside of Europe. Proteomics mAbXmise Kits are not available for sale in all countries.
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DIGESTIF is a soluble recombinant protein scaffold (PBP2x, Penicillin-binding protein 2x from Streptococcus pneumoniae) deleted of its N-ter part and resulting from the collaboration between Biognosys, Promise Proteomics and academic teams1.
DIGESTIF is composed of 11 artificial peptides (iRT) of various hydrophobicity with good ionization.
DIGESTIF is a two-in-one quality control reagent used to check digestion quality & efficiency as well as LC-MS performances during bottom-up proteomic experiments.
1 Lebert, D. and al. (2014). DIGESTIF : A Universal Quality Standard for the Control of Bottom-Up Proteomics Experiments. Journal of Proteome Research, 14(2), 787‑803. https://doi.org/10.1021/pr500834z
